Navelbine ® IV & Navelbine ® Oral - Vinorelbine

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Opening the blister pack

1. Cut the blister pack with scissors along the dotted lines.

2. Gently peel back the blister pack’s white film.

3. Press on the clear plastic to expel the capsule.

(strictly intravenous route)

  • NAVELBINE® can be administered to ambulatory patients.
  • NAVELBINE® can be administered without premedication.
  • NAVELBINE® does not require any particular equipment and may be infused manually, with an intravenous drip, through an implantable port… but always intravenously.
attention ALL THE FOLLOWING RECOMMENDATIONS SHOULD BE STRICTLY FOLLOWED TO PREVENT THE PATIENT FROM ANY LOCAL IRRITATION, PHLEBITIS AND PAIN.

 

Peripheral route

Installation of catheter (gloves are required):

  • Disinfect the injection site (peripheral vein or implantable port).
  • Cannulate a large vein far from articulations and tendinous insertions (not on the side of surgery for Breast Cancer).

 

Checking

Check that the cannula is in the vein by drawing back blood. Infuse around 100-150 ml of saline solution (from the 500 ml bag) to rinse the vein and to verify there is no extravasation.

Short infusion

You can continue the infusion of saline or stop it during administration of NAVELBINE®. NAVELBINE® should be administered over a period between 6 to 10 minutes followed by a thorough flush of the vein with further solution (around 250 ml) to minimize the risk of venous irritation. Remove the catheter from the vein.

NB: In case of a significant dead space due to the use of a programmable pump, do not forget to rinse the tubing.

 

Implantable port

Respect usual procedure for manipulation of the port. Follow the same recommendations of administration as for peripheral administration.

Administration of NAVELBINE® in combination schedules

In combination schedules, it is recommended to use NAVELBINE® first.

  • Do not mix NAVELBINE® in the infusion bag with any other drug.
  • Do not forget the potential premedication(s) for the other drugs.

(CNHIM 2001 tome XXII; Knick VC, Proc. Am. Ass. Cancer research vol 35 March 1994; Adams DJ, Proc. Am. Ass. Cancer research vol 35 March 1994).

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Opening the blister pack

1. Cut the blister pack with scissors along the dotted lines.

2. Gently peel back the blister pack’s white film.

3. Press on the clear plastic to expel the capsule.


(strictly intravenous route)

  • NAVELBINE® can be administered to ambulatory patients.
  • NAVELBINE® can be administered without premedication.
  • NAVELBINE® does not require any particular equipment and may be infused manually, with an intravenous drip, through an implantable port… but always intravenously.
attention ALL THE FOLLOWING RECOMMENDATIONS SHOULD BE STRICTLY FOLLOWED TO PREVENT THE PATIENT FROM ANY LOCAL IRRITATION, PHLEBITIS AND PAIN.

 

Peripheral route

Installation of catheter (gloves are required):

  • Disinfect the injection site (peripheral vein or implantable port).
  • Cannulate a large vein far from articulations and tendinous insertions (not on the side of surgery for Breast Cancer).

 

Checking

Check that the cannula is in the vein by drawing back blood. Infuse around 100-150 ml of saline solution (from the 500 ml bag) to rinse the vein and to verify there is no extravasation.

Short infusion

You can continue the infusion of saline or stop it during administration of NAVELBINE®. NAVELBINE® should be administered over a period between 6 to 10 minutes followed by a thorough flush of the vein with further solution (around 250 ml) to minimize the risk of venous irritation. Remove the catheter from the vein.

NB: In case of a significant dead space due to the use of a programmable pump, do not forget to rinse the tubing.

 

Implantable port

Respect usual procedure for manipulation of the port. Follow the same recommendations of administration as for peripheral administration.

Administration of NAVELBINE® in combination schedules

In combination schedules, it is recommended to use NAVELBINE® first.

  • Do not mix NAVELBINE® in the infusion bag with any other drug.
  • Do not forget the potential premedication(s) for the other drugs.

(CNHIM 2001 tome XXII; Knick VC, Proc. Am. Ass. Cancer research vol 35 March 1994; Adams DJ, Proc. Am. Ass. Cancer research vol 35 March 1994).

 
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